proviron for women

International Non-Proprietary Name (INN) : Proviron for women

Dosage form : film-coated tablets.

Composition : Each coated tablet contains: Active ingredient : proviron for women – 0.5 g Excipients : starch, microcrystalline cellulose, sodium lauryl sulfate, polyvinyl pyrrolidone K 90, purified talc, magnesium stearate, colloidal silicon dioxide, sodium starch glycolate ( type A), E-100 eudrazhit, titanium dioxide, polyethylene glycol 6000, isopropyl alcohol, acetone, water purified.

Description : Round, biconvex tablets, film-coated white or almost white, with Valium on one party.

Pharmacotherapeutic group : protivoprotozoynoe means

Pharmacological properties
proviron for women active against trichomonas, giardia, dysentery amoeba, some anaerobic bacteria (Bacteroides, fuzobakterii, some strains of Clostridium, anaerobic cocci).

Pharmacokinetics
The absorption from the gastrointestinal tract – is high. Bioavailability – 90%. The time to maximum concentration (TC max ) – 1-2 hours.
The connection of the plasma protein – not less than 15%. It penetrates through the blood-brain barrier.
The half-life (T?) -. About 13 hours is displayed in the form of metabolites kidneys (60-70%) and faeces (20-25%), about 5% of the dose is excreted unchanged.

Indications
trichomoniasis, amoebiasis, amoebic dysentery, amoebiasis extraenteric (including amebic liver abscess); giardiasis; prevention of infections caused by anaerobic bacteria, in operations on the colon and in gynecology.

Contraindications:
Hypersensitivity, pregnancy (I trimester), lactation, organic diseases of the central nervous system.

Dosage
If trichomoniasis: Adults – 0.5 g 2 times a day for 5 days. Children – in a single dose of 25 mg / kg.
In amoebic dysentery in adults and children weighing more than 35 kg – 1.5 g 1 time / day, while the body Mahe over 60 kg – 2 g / day. For children weighing less than 35 kg – 40 mg / kg / day. Course – 3 days.
For the treatment of other forms of amebiasis: Adults and children over 12 years – 0.5 g orally in the morning and in the evening for 5-10 days. Single doses Children aged 7-12 years – 0.375g; 1-6 years – 0.25 g; up to 1 year – 0.125 g; multiplicity of purposes – 2 times a day (morning and evening); treatment duration of 5-10 days.
When giardiasis: adults and children weighing more than 35 kg – inside, 1.5 g 1 time per day; children weighing up to 35 kg – 40 mg / kg / day. Duration of treatment – 1-2 days.
Prevention of infections caused by anaerobic bacteria – 0.5-1 g before surgery, after surgery – 0.5 g of 2 times a day for 3-5 days.

Side effects
Headache, dizziness, impairment of consciousness, tremor, rigidity, discoordination movements, seizures, sensory or mixed peripheral neuropathy, nausea, vomiting, diarrhea.

Overdose
Symptoms: epileptiform convulsions, depression, peripheral neuritis. Treatment: symptomatic (diazepam – in convulsions).

Interaction with other drugs
Enhances the effect of coumarin anticoagulants prolong muscle relaxant action of vecuronium bromide. Compatible with alcohol (not inhibit acetaldehyde dehydrogenase).

Cautions
simultaneous treatment of both partners should be the treatment of trichomoniasis.

Form release
coated tablets of 500 mg.
10 tablets in a strip of aluminum foil. On the Strip 1 together with instructions for use placed in a cardboard box. 5 packs of cardboard placed in a cardboard box. men’s health