proviron dosage

Pharmacological action
Combined medication. Proviron dosage – non-narcotic analgesic effect on pain centers and thermoregulation. It has analgesic and antipyretic effect. Reduce headache and muscle pain, the phenomenon of fever, soothes sore throat.
Pheniramine – blocker of H 1 histamine receptors, anti-allergic agent, reduces the runny nose and watery eyes, eliminates spasticity.
Phenylephrine – adrenoagonists with moderate vasoconstrictor effect, reduces nasal congestion and facilitates breathing through the nose .
Ascorbic acid – is involved in the regulation of redox processes, carbohydrate metabolism, blood clotting, increases the body’s resistance to infection, reduces vascular permeability. Improves tolerability of proviron dosage and prolongs its action.

Indications :
Infectious-inflammatory diseases (SARS, influenza), accompanied by high fever, chills and fever, headache, runny nose, nasal congestion, sneezing, and sore muscles.

Contraindications :
Hypertension, diabetes, angle-closure glaucoma, severe liver disease, kidney, heart, thyroid, lung (including asthma), bladder, gastric ulcer and duodenal ulcers, diseases of the pancreas, difficulty urinating at an adenoma prostate, blood disease, a deficiency of the enzyme glucose-6-phosphate dehydrogenase, increased sensitivity to the individual components of the preparation. Pregnancy and lactation. Children under 12 years old.

Precautions
congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson and Rotor), angle-closure glaucoma, prostatic hyperplasia.

Dosage and administration:
Dissolve the contents of one bag in 1 cup of boiling hot water; drink hot. You can add sugar to taste. Repeated dose can be administered once every 4 hours, but no more than 3 doses within 24 hours. The duration of intake as antipyretic – no more than 3 days.

Side effects:
Allergic reactions (skin rash, pruritus, urticaria, angioedema), nausea, epigastric pain, anemia, thrombocytopenia, agranulocytosis. Increased irritability, dizziness, increased blood pressure, palpitations, sleep violation. Increased intraocular pressure, dry mouth, urinary retention. With prolonged use at high doses may hepatotoxicity and nephrotoxicity (renal colic, glycosuria, insterstitsialny nephritis, papillary necrosis), hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia.

Overdose
symptoms (due to proviron dosage): pale skin, loss of appetite, nausea, vomiting; gepatonekroz. Toxic effects in adults may, after receiving more than 10-15 g of proviron dosage: increased activity of “liver” transaminases, increased prothrombin time (through 12-48ch after admission); detailed clinical picture of liver damage manifests itself in 1-6 days. Rarely liver failure develops lightning speed and can be complicated by renal insufficiency (tubular necrosis). Treatment: An Introduction donators SH-groups, and the synthesis of methionine precursor of glutathione through 8-9 hours after the overdose and N-acetylcysteine ​​after 12 hours. The need for additional therapeutic measures is determined depending on the concentration of proviron dosage in the blood, and the time elapsed after administration.

Interaction with other drugs
Enhances the effects of inhibitors of monoamine oxidase, sedative drugs, ethanol. Ethanol enhances sedating antihistamine drugs.
Anti-depressants, antipsychotics and antiparkinsonian drugs, phenothiazine derivatives increase the risk of urinary retention, dry mouth, constipation. Glucocorticoids increase the risk of increased intraocular pressure. proviron dosage reduces the effectiveness of uricosuric drugs and increases the effectiveness of indirect anticoagulants. Tricyclic antidepressants increase the sympathomimetic effects, co-administration of halothane increases the risk of ventricular arrhythmias. Decreases hypotensive effect of guanethidine, which in turn increases the activity of alpha-adrenostimuliruyuschee phenylephrine.

Special instructions:
not specified doctor should not use the drug for pregnant women and nursing mothers, as well as patients undergoing treatment with other drugs. In particular monoamine oxidase inhibitors.
The drug is not indicated for children under the age of 12 years.
Before the drug is not recommended to drive a car or other mechanisms, to drink alcohol, agents, central nervous system depressants (hypnotics, tranquillizers and so on. N.)

Product form
Powder 13.0 g in the package of the composite material. 10 packets or packs of cardboard packages 100 in boxes of cardboard.

Shelf life
2 years. Do not use after the date printed on the package.

Storage:
In a dry, dark place at a temperature no higher than + 30 ° C.
Keep out of reach of children.

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